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  • HIV - stands for Human Immunodeficiency Virus. A virus that weakens a patient’s immune system over time.
  • HIV-1 - the most common type of HIV worldwide.
  • CD4+ T-cell -  a type of cell that helps fight infections. Called CD4+ because of a type of receptor on the surface of the cell
  • combination antiretroviral therapy -  the combination of medicines, or regimen, used to treat HIV infection
  • R5 HIV 1 This type of HIV uses the coreceptor CCR5 (R5 for short) as a coreceptor to blind to and infect human cells.
  • T Cell Count  measurement of the amount of T-cells found in a sample of blood. 
  • CCR5-tropic HIV-1 - the type of HIV-1 that uses the CCR5 coreceptor to attach to CD4+ T-cells.
  • CD4+ T-cell count - the number of CD4+ T-cells in every cubic millimeter of blood.
  • Coreceptor – on the surface of CD4+ T-cells; used by HIV, along with the CD4 receptor, to attach to CD4+ T-cells.
  • Tropism – refers to the type of coreceptor that HIV uses to attach to CD4+ T-cells.
  • Tropism test or tropism assay – test done to determine which type of coreceptor a patient’s HIV uses to attach to a CD4+ T-cell.
  • AIDS – stands for Acquired Immunodeficiency Syndrome. The most severe phase of HIV infection. People with AIDS have such badly damaged immune systems that they get an increasing number of severe illnesses, called opportunistic illnesses
  • Opportunistic infections - infections that occur more frequently and are more severe in individuals with weakened immune systems, including people with HIV