Patients taking SELZENTRY have experienced serious side effects, including liver problems. An allergic reaction may happen before liver problems occur. Stop taking SELZENTRY and call your doctor right away if you get any of the following symptoms: an itchy rash on your body (allergic reaction), your skin or eyes look yellow and/or dark (tea-colored) urine, vomiting and/or upper right stomach area (abdominal) pain. CONTINUED BELOW
When it comes to fighting HIV, new drugs are coming out all the time. SELZENTRY is the only oral medication available that has been designed to target HIV outside the cell. If your viral loads are not where you want them to be, consider talking to your doctor about SELZENTRY.
Get started by printing the questions below. Then take them to your doctor for your next appointment.
If you’ve been newly diagnosed with HIV…
…the following questions can help you start a discussion with your doctor about SELZENTRY and the prescreening test. Print a copy to bring on your next visit.
- What tests do I need? What are they for?
- What is a tropism test? Why is it referred to as a “prescreening test”?
- How is SELZENTRY different from other HIV drugs?
- How is my treatment regimen selected?
- What role could SELZENTRY play in my treatment plan?
- With HIV medications, what side effects are likely?
- Is there anything I should avoid while taking SELZENTRY?
- What should I do if I become pregnant while on SELZENTRY?
- Are there any medicines or supplements I should avoid while taking SELZENTRY?
- What are some of the possible side effects of SELZENTRY?
If you’ve been treated for HIV for a while and still have a detectable viral load…
…you may still have questions about SELZENTRY you’d like to discuss with your doctor. Print a copy to bring on your next visit.
- How is SELZENTRY different from other HIV drugs?
- What role could SELZENTRY play in my treatment plan?
- Should I consider adding SELZENTRY to my treatment plan?
- What tests can be performed to find out if SELZENTRY is an option for me?
- What is a tropism test? Why is it referred to as a “prescreening test”?
- What is my tropism? Do I need a tropism test?
- Will SELZENTRY affect other medicines I am taking?
- Can I eat and drink whatever and whenever I want while I’m taking SELZENTRY?
- What are some of the possible side effects of SELZENTRY?
By prescription only,
IMPORTANT SAFETY INFORMATION
Patients taking SELZENTRY have experienced serious side effects, including liver problems. An allergic reaction may happen before liver problems occur. Stop taking SELZENTRY and call your doctor right away if you get any of the following symptoms:
- an itchy rash on your body (allergic reaction)
- your skin or eyes look yellow and/or dark (tea-colored) urine
- vomiting and/or upper right stomach area (abdominal) pain.
Before you take SELZENTRY, tell your healthcare provider if you have liver problems including:
- history of hepatitis B or C
- have heart problems
- have kidney problems
- have low blood pressure or take medicines to lower blood pressure
- have any other medical condition
- are pregnant or plan to become pregnant
- are breastfeeding or plan to breastfeed
INDICATION AND USAGE
SELZENTRY® (maraviroc) is a CCR5 inhibitor that is used with other HIV medicines to treat CCR5-tropic HIV. SELZENTRY is not recommended in patients with dual/mixed or CXCR4-tropic HIV. It is for adult patients with CCR5-tropic HIV only. A tropism test is needed before starting SELZENTRY. SELZENTRY does not cure HIV infection or AIDS and does not lower the risk of passing HIV to other people.
People taking SELZENTRY may still develop infections, including opportunistic infections or other conditions that happen with HIV infection. The long-term effects of SELZENTRY are not known at this time. It is very important that you stay under the care of your healthcare provider during treatment with SELZENTRY.
People with severe kidney problems or who are on hemodialysis and are taking certain other medications should not take SELZENTRY. Talk to your healthcare provider before taking this medicine if you have kidney problems
Possible serious side effects of SELZENTRY include:
- Liver problems (see above)
- Heart problems, including heart attack
- Low blood pressure when standing up (postural hypertension). Low blood pressure when standing up can cause dizziness or fainting. Do not drive a car or operate heavy machinery if you have dizziness while taking SELZENTRY. Low blood pressure may occur in patients with severe kidney problems
- Changes in your immune system. A condition called Immune Reconstitution Syndrome can happen when you start taking HIV medicines. Your immune system may get stronger and could begin to fight infections that have been hidden in your body such as pneumonia, herpes virus or tuberculosis. Tell your doctor if you develop new symptoms after starting your HIV medicines
- Possible chance of infection or cancer. SELZENTRY affects other immune system cells and, therefore, may increase your chance for getting other infections or cancer
MOST COMMON SIDE EFFECTS
The most common side effects of SELZENTRY include colds, cough, fever, rash, and dizziness. Tell your doctor about any side effect that bothers you or does not go away.
DRUG INTERACTIONS
Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins and herbal supplements. Certain other medicines may affect the levels of SELZENTRY in your blood. Your doctor may need to change your dose of SELZENTRY when you take it with certain medicines.
Do not take products that contain St. John’s Wort (Hypericum perforatum). St. John’s Wort may lower the levels of SELZENTRY in your blood so that it will not work to treat your CCR5-tropic HIV infection.
SELZENTRY is available in 150-mg and 300-mg tablets.
Please see full Prescribing Information including boxed warnings.